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In addition, experimental studies have shown that the elevation of GSH can inhibit the activation of hepatic stellate cells [33], which is a key driving factor for extracellular matrix deposition and fibrosis, thereby preventing the progression of liver fibrosis [34]

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In vivo sensitisation of tumours by rhGH To extend and validate this study in vivo , we decided to use the anticancer drug daunorubicin, as TNF- , one of the main cytokines involved in sepsis (reviewed in Dinarello, 2000), may induce devastating effects after in vivo injection